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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GCFC
All Species:
27.27
Human Site:
S262
Identified Species:
66.67
UniProt:
Q9Y5B6
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5B6
NP_037461.2
917
104804
S262
R
E
D
E
N
D
A
S
D
D
E
D
D
D
E
Chimpanzee
Pan troglodytes
XP_001164401
917
104831
S262
R
E
D
E
N
D
A
S
D
D
E
D
D
D
E
Rhesus Macaque
Macaca mulatta
XP_001094648
917
104997
S262
R
E
D
E
N
D
A
S
D
D
E
D
D
D
E
Dog
Lupus familis
XP_852159
1062
119678
S407
R
E
D
E
N
D
A
S
D
D
E
D
D
D
E
Cat
Felis silvestris
Mouse
Mus musculus
P58501
917
104583
S262
R
E
D
E
N
D
A
S
D
D
E
D
D
D
E
Rat
Rattus norvegicus
XP_001057305
918
104658
S263
R
E
D
E
N
D
A
S
D
D
E
D
D
D
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514256
803
91918
I177
K
I
A
E
E
I
G
I
E
G
S
D
D
E
A
Chicken
Gallus gallus
XP_416707
959
108152
S303
R
E
D
E
N
D
A
S
D
D
E
D
D
D
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001073652
356
39552
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786187
854
97624
E207
K
R
R
Q
A
A
R
E
R
V
D
F
I
P
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.1
84.5
N.A.
95.3
95.6
N.A.
78
82.5
N.A.
21.1
N.A.
N.A.
N.A.
N.A.
30.5
Protein Similarity:
100
99.8
99.2
85.1
N.A.
97.9
97.7
N.A.
83.6
87.4
N.A.
29.7
N.A.
N.A.
N.A.
N.A.
50.7
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
20
100
N.A.
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
40
100
N.A.
0
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
10
10
70
0
0
0
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
70
0
0
70
0
0
70
70
10
80
80
70
0
% D
% Glu:
0
70
0
80
10
0
0
10
10
0
70
0
0
10
70
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% F
% Gly:
0
0
0
0
0
0
10
0
0
10
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
0
10
0
10
0
0
0
0
10
0
0
% I
% Lys:
20
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
70
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% P
% Gln:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
70
10
10
0
0
0
10
0
10
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
70
0
0
10
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _